▦
Biomarker validation
Organize large cohorts, controls and replicates into reproducible TMA layouts for comparative staining and scoring.
Applications
Galileo TMA systems support high-value pathology applications where sample efficiency, standardization and traceability are essential.
✦
Spatial omics
Place multiple tissue samples on a single assay slide to improve sample throughput and reduce high-value assay consumption.
◎
Multiplexing
Build standardized arrays for multiplex immunofluorescence and image analysis across many tissues under identical conditions.
⌖
Digital pathology
Link core position and donor metadata to de-arraying and image-analysis workflows.
◌
Organoids and models
Standardize analysis of preclinical models, spheroids or organoids when compatible with the chosen sample preparation method.
❄
Frozen tissue research
Use the Frozen TMA Module with compatible Galileo systems for applications requiring frozen material.
Why TMA matters for advanced assays
Many modern assays are expensive, tissue-limited and image-analysis intensive. A well-designed TMA can increase comparability and reduce per-sample reagent and slide costs by allowing multiple samples to be processed together.
Design principles
- Use replicate cores when tissue heterogeneity is expected
- Add positive and negative controls
- Include orientation markers or empty positions
- Select core diameter according to assay and tissue availability
- Preserve donor-to-spot traceability for downstream analysis
Design a TMA for your application
ISENET can help define the most appropriate instrument, core size and workflow based on your biomarker, multiplex or spatial omics project.